Vitamins, Minerals, Antioxidants, and Cancer
Vitamins
• Essential
• Perform specific functions in the body
• Precursor: converted into an active vitamin in the body
• Fat-Soluble vitamins
o Vitamin A
o Vitamin D
o Vitamin E
o Vitamin K
• Water-Soluble Vitamins
o B vitamins
o Vitamin C
Fat-Soluble Vitamins
• Stored extensively in tissue
• Higher risk for toxicity
Water-Soluble Vitamins
• Easily absorbed and excreted
• Not stored extensively in tissue (except B12)
Minerals
Essential Minerals
•Calcium
•Phosphorus
•Magnesium
•Iron
•Zinc
•Fluoride
•Lodine
•Selenium
•Copper
•Manganese
•Chromium
•Molybdenum
•Sodium
•Potassium
•Chloride
Charged Minerals
• Can combine with minerals of the opposite charge
• Electrical power for muscle contraction and nerve reaction
• Help maintain fluid and acid/base balance
• Initiate enzyme activity
Antioxidants
Free Radical
• Atom that has lost an electron
• Produced by: everyday metabolism and toxic substances
• Play a role in
o Heart Disease
o Cancer
o Emphysema
o Bronchitis
o Premature aging
Antioxidant Vitamins
• Donate electrons to stabilize free radicals
• Vitamin A and Beta-carotene
• Vitamin C
• Vitamin E
• Others
Phytochemicals
• Plant chemicals that contain disease-preventing compounds
• Not yet classified as nutrients
• >2000 have been identified
• >100 in one serving of vegetables
Red
• Lycopene, Anthocyanins
• Maintain heart health
• Maintain memory function
• Lower risk of some cancers
• Maintain urinary tract health
Yellow/Orange
• Vitamin C, Carotenoids, Bioflavonoids
• Maintain heart health
• Maintain vision health
• Maintain a healthy immune system
• Lower risk of some cancers
White
• Allyl Sulfides
• Maintain heart health
• Maintain healthy cholesterol levels
• Lower risk of some cancers
Green
• Lutein, Indoles
• Lower risk of some cancers
• Maintain vision health
• Maintain strong bones and teeth
Blue-Purple
• Anthocyanins, Phenolics
• Lower risk of some cancers
• Maintain urinary tract health
• Maintain memory function
• Anti-aging
Others
• Soy Beans, the “Miracle Bean”
o Isoflavones, Saponins
o Decreased risk for heart disease
o Decreased risk for cancer
o May help prevent osteoporosis and reduce symptoms of menopause
• Green tea
o Flavonoids
o Suppress cancer advancement
o Lower LDL and increase HDL cholesterol
Supplements and Extracts
• “No evidence that individual phytochemicals extracted from food benefit health”
• “No evidence that vegetable extracts benefit health”
Nutrition and Cancer
Cancer
• Abnormal cells grow out of control
• Second leading cause of death in U.S.
Cancer Development
• Initiation – alternation of DNA
• Promotion – increased number of abnormal cells
• Progression – uncontrolled growth
Fighting Cancer Through Diet
• Achieve and maintain a healthy weight
• Eat a varied diet
• Increase fruits and vegetables
• Eat more high fiber foods
• Decrease total fat intake
• Limit consumption of alcohol
• Limit consumption of salt-cured, smoked, pickled, and nitrite-preserved foods
Cancer Treatment
“Unorthodox cures should not substitute for conventional treatments”